Synthesis, Spectroscopic Studies and Crystal Structure of (E)-2-(2,4-Dihydroxybenzylidene)thiosemicarbazone and (E)-2-[(1 H-Indol-3-yl)methylene]thiosemicarbazone

Abstract

Thiosemicarbazone Schiff bases (1 and 2) derived from 2,4-dihydroxybenzaldehyde, indoline-3-carbaldehyde and thiosemicarbazone have been synthesized and their structures were elucidated by elemental analysis, FT-IR, 1H NMR, 13C NMR and UV-visible spectroscopic techniques. The structures of compounds 1 and 2 have also been examined cyrstallographically. The title compounds 1 and 2 crystallize in the monoclinic space group C2/c and triclinic space group P over(1, ̄), with unit cell parameters: a = 21.421(1) and 7.233(1), b = 4.131(1) and 11.166(1), c = 24.942(2) and 13.648(1) Å, V = 1856.1(2) and 1019.5(1) Å3, D<inf>x</inf> = 1.512 and 1.422 g cm-3 and Z = 8 and 4, respectively. © 2008 Elsevier B.V. All rights reserved.